Formulation and investigation of turmeric extract and sodium benzoate loaded capsules

Authors

  • Ildikó Bácskay Department of Pharmaceutical Technology; Doctoral School of Pharmaceutical Sciences; Institute of Healthcare Industry, University of Debrecen, Nagyerdei Körút 98, 4032 Debrecen, Hungary
  • Dávid Sinka Department of Pharmaceutical Technology; Doctoral School of Pharmaceutical Sciences; Institute of Healthcare Industry, University of Debrecen, Nagyerdei Körút 98, 4032 Debrecen, Hungary
  • Liza Józsa Department of Pharmaceutical Technology; Doctoral School of Pharmaceutical Sciences; Institute of Healthcare Industry, University of Debrecen, Nagyerdei Körút 98, 4032 Debrecen, Hungary
  • Gábor Vasas Doctoral School of Pharmaceutical Sciences; Department of Pharmacognosy, University of Debrecen, Nagyerdei körút 98, 4032 Debrecen, Hungary
  • Zoltán Újhelyi Department of Pharmaceutical Technology; Doctoral School of Pharmaceutical Sciences; Institute of Healthcare Industry, University of Debrecen, Nagyerdei Körút 98, 4032 Debrecen, Hungary
  • Pálma Fehér Department of Pharmaceutical Technology; Doctoral School of Pharmaceutical Sciences; Institute of Healthcare Industry, University of Debrecen, Nagyerdei Körút 98, 4032 Debrecen, Hungary
  • Béla Juhász Department of Pharmacology and Pharmacotherapy, University of Debrecen, Nagyerdei körút 98, 4032 Debrecen, Hungary
  • Zoltán Szilvássy Department of Pharmacology and Pharmacotherapy, University of Debrecen, Nagyerdei körút 98, 4032 Debrecen, Hungary

DOI:

https://doi.org/10.33892/aph.2021.91.11-20

Keywords:

Curcuma longa, Turmeric, Curcumin, Sodium benzoate, HPMC capsule

Abstract

Turmeric has been studied and used as a plant derivate active ingredient for centuries. Several effects of turmeric have been described, however the poor solubility of its active ingredients during the formulation development may limit oral applicability. The aim of research was to involve the development of a dietary supplement of a hard capsule containing turmeric (Curcuma longa) (ground powder from the root standardized to curcuminoid content) and sodium benzoate. The manufacturing technology and the analytic method of the formulation have been developed. Formulation studies according to the Ph. Hg. VIII. standards have been performed. The product may have insulin sensitizing and memory enhancing effects, related animal studies are ongoing.

Published

2021-06-15

How to Cite

(1)
Bácskay, I.; Sinka, D.; Józsa, L.; Vasas, G.; Újhelyi, Z.; Fehér, P.; Juhász, B.; Szilvássy, Z. Formulation and Investigation of Turmeric Extract and Sodium Benzoate Loaded Capsules. Acta Pharm Hung 2021, 91, 11-20.

Issue

Section

Original Research Articles